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Orthokine is an autologous conditioned serum for osteoarthritis , developed in Germany by a molecular biologist and spinal surgeon. It focuses on increasing the body’s natural anti-inflammatory factors. That is, Interleukin 1 receptor antagonist (IL-1RA), as well as other growth factors. Osteoarthritic joints have high concentrations of interleukin 1 (IL1) which is understood to damage cartilage in joints. IL-1RA blocks the IL1, preventing damage to the joint while growth factors attempt to heal damaged tissue.